Automatic antidote delivery device (A2d2) detects and treats opioid overdose.
With our innovative closed-loop system, Rescue Biomedical is revolutionizing the approach to opioid overdose emergencies.
We help those with oud
Our solution specifically targets individuals with Opioid Use Disorder (OUD), a condition characterized by a problematic pattern of opioid use leading to significant clinical impairment or distress. These individuals may have developed their dependency through various means, including chronic pain medication, cancer treatment, or even the pressures faced by college students.
As OUD continues to ravage communities, there is an urgent need for effective harm reduction strategies. Rescue Biomedical is at the forefront of this battle, driven by a passion for creating real change and saving lives.
Solution
The A2D2 is designed to automatically detect and treat opioid overdoses.
Our discreet wrist-worn device integrates continuous physiological monitoring with a needle-free naloxone injector, enabling rapid, autonomous intervention when an overdose is detected.
The A2D2 would be the first fully wearable, closed-loop system that eliminates the need for bystander intervention. It distinguishes itself by (1) utilizing near-infrared spectroscopy technology for rapid and precise detection of opioid-induced impairment of oxygenation, (2) offering a non-invasive wearable form factor, and (3) providing autonomous naloxone delivery.
Overdose Detection
Antidote delivery
Emergency Alert
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The wearable detection device utilizes near-infrared spectroscopy (NIRS), an advanced sensing technology that measures how light is absorbed by blood in the tissue, enabling continuous, real-time tracking of oxygen saturation trends rather than relying on single-point readings. By integrating these NIRS signals with heart rate, respiration rate, and movement patterns, the system identifies the characteristic physiological signature of opioid-induced impairment of oxygenation with improved sensitivity and reduced false alarms.
When an overdose is detected, the device initiates a short countdown, during which the user can cancel the alert if it is a false detection.
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Upon detecting opioid-induced impairment of oxygenation, the A2D2 automatically activates its needle-free, micro-propellant naloxone injector without requiring any bystander involvement. By delivering naloxone at the earliest physiological sign of overdose, before respiratory arrest becomes prolonged, the device rapidly restores normal breathing and stabilizes the user. Because A2D2 intervenes during the critical early window when oxygen levels first fall, it reduces the duration of brain hypoxia, substantially improves the likelihood of survival, and prevents the overdose from progressing to the severe complications that often require intensive or extended hospital care.
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Once an overdose is confirmed, A2D2 activates a multi-layer notification system to ensure timely support. The device provides prompts to the user, and if there is no response, it alerts the user’s designated contacts with essential information about the situation. It also notifies Rescue Biomedical, which will coordinate with EMS for additional medical intervention. All notification preferences are customizable during device setup.